Recognize the progression
Early (1–5 days)
- ▸Fever and chills
- ▸Severe muscle aches (thighs, hips, back)
- ▸Headache
- ▸Fatigue
- ▸Nausea, vomiting, diarrhea
Late (4–10 days)
- ▸Coughing
- ▸Shortness of breath
- ▸Chest tightness
- ▸Fluid in the lungs (HPS)
- ▸Rapid clinical deterioration
Case fatality for HPS in the United States historically ranges from 35–40%. Early hospitalization significantly improves outcomes.
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